2024
Uckeley ZM, Duboeuf M, Gu Y, Erny A, Mazelier M, Lüchtenborg C, Winter SL, Schad P, Mathieu C, Koch J, Boulant S, Chlanda P, Maisse C, Brügger B, and Lozach PY. “Glucosylceramide in bunyavirus particles is essential for virus binding to host cells” Cell. Mol. Life Sci. 81(1):71
2023
Goellner S, Enkavi G, Prasad V, Denolly S, Eu S, Mizzon G, Witte L, Kulig W, Uckeley ZM, Lavacca TM, Haselmann U, Lozach PY, Brügger B, Vattulainen I, and Bartenschlager R. “Zika virus prM protein contains cholesterol-binding motifs required for virus entry and assembly” Nat. Com. 14(1):7344
Gondelaud F, Lozach PY, and Longhi S. “Viral amyloids: New opportunities for antiviral therapeutic strategies” Curr. Opin. Struct. Biol. 83:102706
Gu Y and Lozach PY. “Illuminating bunyavirus entry into host cells with fluorescence” Mol. Microbiol. 121(4):671-8
Koch J, Xin Q, Obr M, Schäfer A, Rolfs N, Anagho HA, Kudulyte A, Woltereck L, Kummer S, Campos J, Uckeley ZM, Bell-Sakyi L, Kräusslich HG, Schur FKM, Acuna C, and Lozach PY. “The phenuivirus Toscana virus makes an atypical use of vacuolar acidity to enter host cells” PLoS Pathog. 19(8):e1011562
2022
Koch J, Uckeley ZM, and Lozach PY. “SARS-CoV-2 uses different entry routes to infect host cells” Med. Sci. 38(5):419-22
Windhaber S, Xin Q, Uckeley ZM, Koch J, Obr M, Garnier C, Luengo-Guyonnot C, Duboeuf M, Schur FKM, and Lozach PY. “The orthobunyavirus Germiston enters host cells from late endosomes” J. Virol. 96(5):e02146-21
2021
Koch J, Uckeley ZM, and Lozach PY. “SARS-CoV-2 variants as super cell fusers: Cause or consequence of COVID-19 severity?” EMBO J. 40(24):e110041
Peng K and Lozach PY. “Rift Valley fever virus: a new avenue of research on the biological functions of amyloids?” Future Virol. 16(10):677-89
Koch J, Uckeley ZM, Doldan P, Stanifer M, Boulant S, and Lozach PY. “TMPRSS2 expression dictates the entry route used by SARS-CoV-2 to infect host cells” EMBO J. 40(16):e107821
Windhaber S, Xin Q, and Lozach PY. “Orthobunyaviruses: from virus binding to penetration into mammalian host cells” Viruses 13(5):872
Léger P and Lozach PY. “Rift Valley fever virus and the amazing NSs protein”. Med. Sci. 37:601-8
Koch J, Xin Q, Tischler ND, and Lozach PY. “Entry of phenuiviruses into mammalian host cells” Viruses 13(2):299
2020
Lozach PY. “Cell biology of viral infections” Cells 9:2431
Léger P, Nachman E, Richter K, Tamietti C, Koch J, Burk R, Kummer S, Xin Q, Stanifer M, Bouloy M, Boulant S, Kräusslich HG, Montagutelli X, Flamand M, Nussbaum-Krammer C, and Lozach PY. “NSs amyloid formation is associated with the virulence of Rift Valley fever virus in mice” Nat. Commun. 11(1):3281
Woelfl F, Léger P, Oreshkova N, Pahmeier F, Windhaber S, Koch J, Stanifer M, Roman Sosa G, Uckeley ZM, Rey FA, Boulant S, Kortekaas J, Wichgers Schreur PJ, and Lozach PY. “Novel Toscana virus reverse genetics system establishes NSs as an antagonist of type I interferon responses” Viruses 12(4):400
Li S, Li H, Zhang YL, Xin Q, Guan ZQ, Chen X, Zhang XA, Li XK, Xiao GF, Lozach PY, Cui J, Liu W, Zhang LK, and Peng K. “SFTSV infection induces BAK/BAX-dependent mitochondrial DNA release to trigger NLRP3 inflammasome activation” Cell Rep. 30:4370-85
2019
Uckeley ZM, Moeller R, Kühn LI, Nilsson E, Robens C, Lasswitz L, Lindqvist R, Lenman A, Passos V, Voß Y, Sommerauer C, Kampmann M, Goffinet C, Meissner F, Överby AK, Lozach PY, and Gerold G. “Quantitative proteomics of Uukuniemi virus-host cell interactions reveals GBF1 as proviral host factor for phleboviruses” Mol. Cell. Proteomics 18(12):2401-17
Uckeley ZM, Koch J, Tischler ND, Léger P, Lozach PY. “Cell biology of phlebovirus entry” Virologie 23(3):176-87
Li S, Zhu X, Guan Z, Huang W, Kortekaas J, Lozach PY, and Peng K. “NSs filament formation is important but not sufficient for RVFV virulence in vivo”. Viruses 11(9)
Ashtikar M, Mäder K, Klein K, Wunderlich K, Lozach PY, Gao F, Mende S, Strasser C, Dennison T, Marenchino M, and Wacker MG. “LOEWE workshop particle characterization in medicine and biology” Pharm. Front. 1: e190002
2018
Hoffmann A, Mazelier M, Léger P, and Lozach PY. “Deciphering virus entry with fluorescently labeled viral particles” Methods Mol. Biol. 1836:159-83
Lozach PY. “Early virus-host cell interactions” J. Mol. Biol. 430(17):2555-6
2016
Mazelier M, Rouxel RN, Zumstein M, Mancini R, Bell-Sakyi L, and Lozach PY. “Uukuniemi virus as a tick-borne virus model” J. Virol. 90(15):6784-98
Albornoz A, Hoffmann AB, Lozach PY, and Tischler ND. “Early bunyavirus-host cell interactions” Viruses 8(5)
Léger P, Tetard M, Youness B, Cordes N, Rouxel RN, Flamand M, and Lozach PY. “Differential use of the C-type lectins L-SIGN and DC-SIGN for phlebovirus endocytosis” Traffic 17(6):639-56
2015
Acuña R, Bignon E, Mancini R, Lozach PY, and Tischler ND. “Acidification triggers Andes hantavirus membrane fusion and rearrangement of Gc into a stable post-fusion homotrimer” J. Gen. Virol. 96(11):3192-7
Léger L and Lozach PY. “Bunyaviruses: from transmission by arthropods to virus entry into the mammalian host first-target cells” Future Virol. 10(7):859-881
Boulant S, Stanifer M, and Lozach PY. “Dynamics of Virus-Receptor Interactions in Virus Binding, Signaling, and Endocytosis” Viruses 7(6):2794-2815
Meier R, Mazelier M, and Lozach PY. “High-throughput small interfering RNA screens: when small interfering RNAs behave like microRNA” Med. Sci. 31(3):247-249
2014
Meier R, Franceschini A, Horvath P, Tetard M, Mancini R, von Mering C, Helenius A, and Lozach PY. “Genome-wide small interfering RNA screens reveal VAMP3 as a novel host factor required for Uukuniemi virus late penetration” J. Virol. 88(15), 8565-78
Acuña R, Cifuentes-Muñoz N, Márquez CL, Bulling M, Klingström J, Mancini R, Lozach PY, and Tischler ND. “Hantavirus Gn and Gc glycoproteins self-assemble into virus-like particles” J. Virol. 88(4), 2344-8
2013
Goncalves AR, Moraz ML, Pasquato A, Helenius A, Lozach PY, and Kunz S. “Role of DC-SIGN in Lassa virus entry into human dendritic cells” J. Virol. 87(21), 11504-15
Mercer J and Lozach PY. “Cellular protein disposal system assists poxvirus genome uncoating” Med. Sci. 29(6-7):561-3
Barriga GP, Martinez-Valdebenito C, Galeno H, Ferrés M, Lozach PY, and Tischler ND. “A rapid method for infectivity titration of Andes hantavirus using flow cytometry” J. Virol. Methods 193(2):291-4
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Pierre-Yves Lozach